Carotenoids are substantially hydrophobic antioxidants.Hydrophobicity is this context is rather a disadvantage, because their utilization in medicine as antioxidants or in food chemistry as Lip Makeup colorants would require some water dispersibility for Hygiene their effective uptake or use in many other ways.In the past 15 years several attempts were made to synthetize partially hydrophilic carotenoids.This review compiles the recently synthetized hydrophilic carotenoid derivatives.